药物化学系

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赵育

作者:金飞     日期:2021-10-26   点击数:2280  

师资介绍

赵育,男,汉族,1976年9月生,研究员,博士,药物化学系副主任

研究方向:

糖化学、药物化学

社会学术兼职:

中国药学会会员,江苏省高新技术企业评审专家,江苏省政府采购专家,“春晖杯”生物医药组评委。

基金项目:

1)骨化三醇软胶囊制剂的开发,2020.03-2021.0235万元,南通华山药业有限公司

2)抗癫痫药左乙拉西坦的研制,2020.12-2022.068万元,雅本化学股份有限公司

代表性论文:

  1. Li Zhu, Ruihan Zhao, Yu Li, Gongqing Liu, Yu Zhao*, CtD Strategy to Construct Stereochemically Complex and Structually Diverse Compounds from Griseofulvin, Chemical Communications, 2021, DOI: 10.1039/D1CC04007C

  2. Li Zhu, Yapeng Lu, Yu Li, Yong Ling, Yu Zhao*, Synthesis and Evaluation of Diphyllin β-Hydroxyl Amino Derivatives as Novel V-ATPase InhibitorsChemical Biology & Drug Design, 2021, 98(4), 674-682

  3. Xiaofeng Bao, Ziyi Liu, Min Ni, Chao Xia, Shunxin Xu, Shengju Yang,  Yu Zhao*, Synthesis and Assessment of 3-Substituted Phenazines as Novel Antichlamydial Agents, Medicinal Chemistry, 2020, 3 (16), 413-421

  4. Rui Cai, Li Zhu, Weidong Shen, Yu Zhao*, Synthesis, Cytotoxicity and Anti-invasion Activity of Three Natural Diphyllin L-arabinopyranosides, Fitoterapia, 2019, 137, 104198

  5. Yapeng Lu, Lu Wang, Xinyang Wang, Haoliang Yuan, Yu Zhao*, Divergent de novo Synthesis of 2, 4, 5-Trideoxyhexopyranosides Derivatives of Podophyllotoxin as Anticancer Agents, Future Medicinal Chemistry, 2019, 11, 23, 3015-3027

发明专利:

 1.  Cleistanthin-A衍生物及其制备方法和用途,ZL 201410555794.8

 2.  236-三脱氧糖基去甲表鬼臼毒素化合物及其制备方法和用途,ZL 201811483180.8

 3. 一种山荷叶素杂环衍生物及其制备方法和应用,CN 202010075949.3

 4. 一种山荷叶素醚类衍生物及其制备方法和应用,CN 202010145928.4